No.	InterPro name	Number of genes	Number of Ensembl hits	No.	InterPro name	Number of genes	Number of Ensembl hits
1	IPR011009 Protein kinase-like domain	599	773	251	IPR020422 Dual specificity phosphatase, subgroup, catalytic domain	47	109
2	IPR000719 Protein kinase, catalytic domain	556	722	252	IPR000859 CUB	47	637
3	IPR002290 Serine/threonine-protein kinase domain	554	719	253	IPR020904 Short-chain dehydrogenase/reductase, conserved site	47	65
4	IPR017442 Serine/threonine-protein kinase-like domain	549	716	254	IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2	47	109
5	IPR020635 Tyrosine-protein kinase, catalytic domain	543	696	255	IPR002172 Low-density lipoprotein (LDL) receptor class A repeat	47	1211
6	IPR000276 GPCR, rhodopsin-like, 7TM	477	4313	256	IPR000571 Zinc finger, CCCH-type	47	285
7	IPR007110 Immunoglobulin-like	468	1413	257	IPR001878 Zinc finger, CCHC-type	47	194
8	IPR017452 GPCR, rhodopsin-like superfamily	461	573	258	IPR005828 General substrate transporter	46	69
9	IPR007087 Zinc finger, C2H2-type	442	8566	259	IPR018159 Spectrin/alpha-actinin	46	382
10	IPR001245 Serine-threonine/tyrosine-protein kinase	431	1961	260	IPR008365 Prostanoid receptor	46	187
11	IPR003599 Immunoglobulin subtype	428	1408	261	IPR001627 Semaphorin/CD100 antigen	46	112
12	IPR017441 Protein kinase, ATP binding site	407	530	262	IPR001766 Transcription factor, fork head	46	278
13	IPR015880 Zinc finger, C2H2-like	402	3429	263	IPR022364 F-box domain, Skp2-like	46	52
14	IPR009057 Homeodomain-like	397	518	264	IPR000595 Cyclic nucleotide-binding domain	46	227
15	IPR003598 Immunoglobulin subtype 2	396	1174	265	IPR003439 ABC transporter-like	46	155
16	IPR008271 Serine/threonine-protein kinase, active site	346	445	266	IPR002165 Plexin	45	97
17	IPR001841 Zinc finger, RING-type	333	760	267	IPR019955 Ubiquitin supergroup	45	66
18	IPR013151 Immunoglobulin	330	1065	268	IPR000340 Dual specificity phosphatase, catalytic domain	45	60
19	IPR013106 Immunoglobulin V-set	320	655	269	IPR016137 Regulator of G protein signalling superfamily	45	66
20	IPR013032 EGF-like region, conserved site	305	2387	270	IPR008145 Guanylate kinase/L-type calcium channel	45	64
21	IPR003596 Immunoglobulin V-set, subgroup	299	516	271	IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal	45	56
22	IPR016024 Armadillo-type fold	298	416	272	IPR001214 SET domain	45	126
23	IPR001849 Pleckstrin homology domain	297	1166	273	IPR001507 Zona pellucida sperm-binding protein	44	91
24	IPR011046 WD40 repeat-like-containing domain	268	356	274	IPR020454 Diacylglycerol/phorbol-ester binding	44	222
25	IPR001611 Leucine-rich repeat	268	1714	275	IPR000301 Tetraspanin, subgroup	44	227
26	IPR001680 WD40 repeat	265	1805	276	IPR011500 GPCR, family 3, nine cysteines domain	44	57
27	IPR001452 Src homology-3 domain	251	2234	277	IPR002343 Paraneoplastic encephalomyelitis antigen	44	198
28	IPR019781 WD40 repeat, subgroup	241	1215	278	IPR000195 Rab-GAP/TBC domain	44	244
29	IPR018957 Zinc finger, C3HC4 RING-type	236	282	279	IPR002397 Cytochrome P450, B-class	44	207
30	IPR008957 Fibronectin type III domain	234	973	280	IPR001487 Bromodomain	44	431
31	IPR000504 RNA recognition motif domain	233	1516	281	IPR001005 SANT domain, DNA binding	44	77
32	IPR001356 Homeobox	232	868	282	IPR000626 Ubiquitin	43	111
33	IPR001806 Ras GTPase	230	1112	283	IPR000355 Chemokine receptor	43	232
34	IPR017986 WD40-repeat-containing domain	227	336	284	IPR000342 Regulator of G protein signalling	43	354
35	IPR000533 Tropomyosin	221	860	285	IPR001007 von Willebrand factor, type C	43	354
36	IPR009053 Prefoldin	216	360	286	IPR000306 Zinc finger, FYVE-type	43	88
37	IPR019782 WD40 repeat 2	216	799	287	IPR016197 Chromo domain-like	43	66
38	IPR003593 ATPase, AAA+ type, core	215	308	288	IPR011616 bZIP transcription factor, bZIP-1	42	49
39	IPR018247 EF-Hand 1, calcium-binding site	215	486	289	IPR000953 Chromo domain/shadow	42	120
40	IPR006210 Epidermal growth factor-like	209	1758	290	IPR016181 Acyl-CoA N-acyltransferase	42	55
41	IPR013098 Immunoglobulin I-set	207	867	291	IPR000608 Ubiquitin-conjugating enzyme, E2	42	102
42	IPR011511 Variant SH3	204	346	292	IPR003095 Heat shock protein DnaJ	41	136
43	IPR018249 EF-HAND 2	203	385	293	IPR001073 Complement C1q protein	41	279
44	IPR020683 Ankyrin repeat-containing domain	198	580	294	IPR000826 Formyl/methionyl peptide receptor	41	170
45	IPR002048 Calcium-binding EF-hand	197	608	295	IPR001839 Transforming growth factor-beta, C-terminal	41	102
46	IPR000742 Epidermal growth factor-like, type 3	196	1068	296	IPR006026 Peptidase, metallopeptidase	41	54
47	IPR018248 EF-hand	195	560	297	IPR002353 Type II antifreeze protein	41	189
48	IPR005225 Small GTP-binding protein domain	195	228	298	IPR018122 Transcription factor, fork head, conserved site	41	72
49	IPR002110 Ankyrin repeat	195	3606	299	IPR002233 Adrenergic receptor	41	142
50	IPR003579 Ras small GTPase, Rab type	194	235	300	IPR002455 GPCR, family 3, gamma-aminobutyric acid receptor, type B	40	154
51	IPR003961 Fibronectin, type III	193	1740	301	IPR008144 Guanylate kinase	39	108
52	IPR013753 Ras	188	228	302	IPR006553 Leucine-rich repeat, cysteine-containing subtype	39	218
53	IPR003591 Leucine-rich repeat, typical subtype	186	1585	303	IPR006687 Small GTPase SAR1-type	39	43
54	IPR019775 WD40 repeat, conserved site	185	370	304	IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site	39	256
55	IPR011333 BTB/POZ fold	185	248	305	IPR002957 Keratin, type I	39	198
56	IPR008973 C2 calcium/lipid-binding domain, CaLB	184	354	306	IPR018490 Cyclic nucleotide-binding-like	38	68
57	IPR001881 EGF-like calcium-binding	183	1038	307	IPR018200 Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site	38	85
58	IPR020472 G-protein beta WD-40 repeat	182	632	308	IPR012679 Laminin G, subdomain 1	38	90
59	IPR001478 PDZ/DHR/GLGF	181	1511	309	IPR001757 ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter	38	381
60	IPR017970 Homeobox, conserved site	181	214	310	IPR010916 TonB box, conserved site	38	42
61	IPR003577 Ras small GTPase, Ras type	180	219	311	IPR000405 Galanin receptor	38	112
62	IPR017907 Zinc finger, RING-type, conserved site	176	216	312	IPR000449 Ubiquitin-associated/translation elongation factor EF1B, N-terminal	38	51
63	IPR000210 BTB/POZ-like	175	414	313	IPR001277 CXC chemokine receptor, type 4	38	160
64	IPR006209 EGF	173	943	314	IPR001565 Synaptotagmin	37	151
65	IPR003578 Small GTPase, Rho type	166	205	315	IPR019821 Kinesin, motor region, conserved site	37	42
66	IPR013684 Mitochondrial Rho-like	162	200	316	IPR011024 Gamma-crystallin-related	37	64
67	IPR000008 C2 calcium-dependent membrane targeting	160	611	317	IPR000569 HECT	37	158
68	IPR001781 Zinc finger, LIM-type	150	1042	318	IPR003938 Potassium channel, voltage-dependent, EAG/ELK/ERG	37	246
69	IPR000047 Helix-turn-helix motif, lambda-like repressor	142	342	319	IPR000834 Peptidase M14, carboxypeptidase A	37	242
70	IPR002286 P2 purinoceptor	140	649	320	IPR005834 Haloacid dehalogenase-like hydrolase	37	51
71	IPR011011 Zinc finger, FYVE/PHD-type	139	208	321	IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site	37	41
72	IPR020479 Homeobox, eukaryotic	138	474	322	IPR009150 Neuropeptide W receptor	37	163
73	IPR019734 Tetratricopeptide repeat	136	1073	323	IPR001632 G-protein, beta subunit	36	113
74	IPR018029 C2 membrane targeting protein	132	254	324	IPR006552 VWC out	36	110
75	IPR002041 Ran GTPase	132	226	325	IPR004841 Amino acid permease domain	36	55
76	IPR003656 Zinc finger, BED-type predicted	130	227	326	IPR001138 Zn(2)-C6 fungal-type DNA-binding domain	36	46
77	IPR005821 Ion transport	129	236	327	IPR000408 Regulator of chromosome condensation, RCC1	36	394
78	IPR013069 BTB/POZ	129	178	328	IPR001496 SOCS protein, C-terminal	36	105
79	IPR011701 Major facilitator superfamily	127	181	329	IPR000566 Lipocalin/cytosolic fatty-acid binding protein domain	36	56
80	IPR008985 Concanavalin A-like lectin/glucanase	127	258	330	IPR023780 Chromo domain	36	49
81	IPR000611 Neuropeptide Y receptor	126	565	331	IPR010987 Glutathione S-transferase, C-terminal-like	36	47
82	IPR006688 ADP-ribosylation factor	122	145	332	IPR004087 K Homology	36	130
83	IPR001092 Helix-loop-helix DNA-binding domain	122	410	333	IPR000014 PAS	35	127
84	IPR000152 EGF-type aspartate/asparagine hydroxylation site	114	566	334	IPR002350 Proteinase inhibitor I1, Kazal	35	95
85	IPR001870 B302/SPRY domain	114	128	335	IPR000175 Sodium:neurotransmitter symporter	35	548
86	IPR011598 Helix-loop-helix DNA-binding	114	134	336	IPR006162 Phosphopantetheine attachment site	35	41
87	IPR018355 SPla/RYanodine receptor subgroup	114	142	337	IPR000795 Protein synthesis factor, GTP-binding	35	174
88	IPR010993 Sterile alpha motif homology	113	171	338	IPR005819 Histone H5	35	107
89	IPR014756 Immunoglobulin E-set	113	302	339	IPR006028 Gamma-aminobutyric acid A receptor	35	186
90	IPR000483 Cysteine-rich flanking region, C-terminal domain	112	189	340	IPR002424 Alcohol dehydrogenase, insect family	35	131
91	IPR008266 Tyrosine-protein kinase, active site	111	136	341	IPR017974 Claudin, conserved site	34	35
92	IPR016187 C-type lectin fold	111	267	342	IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase	34	124
93	IPR013026 Tetratricopeptide repeat-containing	110	161	343	IPR003129 Laminin G, thrombospondin-type, N-terminal	34	44
94	IPR008936 Rho GTPase activation protein	109	133	344	IPR011047 Quinonprotein alcohol dehydrogenase-like	34	38
95	IPR018097 EGF-like calcium-binding, conserved site	109	555	345	IPR001879 GPCR, family 2, extracellular hormone receptor domain	34	111
96	IPR003877 SPla/RYanodine receptor SPRY	108	137	346	IPR000500 Connexin	34	199
97	IPR013111 EGF, extracellular	108	334	347	IPR018303 ATPase, P-type phosphorylation site	34	48
98	IPR000315 Zinc finger, B-box	107	374	348	IPR014778 Myb, DNA-binding	34	62
99	IPR003879 Butyrophylin-like	107	489	349	IPR018111 K Homology, type 1, subgroup	34	130
100	IPR012336 Thioredoxin-like fold	106	176	350	IPR006671 Cyclin, N-terminal	34	53
101	IPR014001 DEAD-like helicase	106	123	351	IPR019750 Band 4.1 family	34	162
102	IPR000980 SH2 motif	103	890	352	IPR000007 Tubby, C-terminal	34	72
103	IPR003006 Immunoglobulin/major histocompatibility complex, conserved site	102	130	353	IPR017948 Transforming growth factor beta, conserved site	34	44
104	IPR001965 Zinc finger, PHD-type	102	201	354	IPR001590 Peptidase M12B, ADAM/reprolysin	34	78
105	IPR020846 Major facilitator superfamily domain	101	146	355	IPR003968 Potassium channel, voltage dependent, Kv	34	167
106	IPR006574 SPRY-associated	100	114	356	IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain	33	46
107	IPR009003 Peptidase cysteine/serine, trypsin-like	100	141	357	IPR013162 CD80-like, immunoglobulin C2-set	33	48
108	IPR013847 POU	100	282	358	IPR002909 Cell surface receptor IPT/TIG	33	189
109	IPR003595 Protein-tyrosine phosphatase, catalytic	99	144	359	IPR001251 Cellular retinaldehyde-binding/triple function, C-terminal	33	146
110	IPR008979 Galactose-binding domain-like	99	141	360	IPR013092 Connexin, N-terminal	33	67
111	IPR010989 t-SNARE	98	124	361	IPR002928 Myosin tail	33	44
112	IPR001254 Peptidase S1/S6, chymotrypsin/Hap	97	393	362	IPR000873 AMP-dependent synthetase/ligase	33	49
113	IPR000048 IQ motif, EF-hand binding site	97	648	363	IPR001390 Gamma-aminobutyric-acid A receptor, alpha subunit	33	226
114	IPR001660 Sterile alpha motif domain	95	257	364	IPR000929 Dopamine receptor	33	119
115	IPR000387 Protein-tyrosine/Dual-specificity phosphatase	94	137	365	IPR009079 Four-helical cytokine-like, core	33	37
116	IPR004827 Basic-leucine zipper (bZIP) transcription factor	94	221	366	IPR001064 Beta/gamma crystallin	33	617
117	IPR001304 C-type lectin	91	607	367	IPR011497 Protease inhibitor, Kazal-type	33	53
118	IPR001314 Peptidase S1A, chymotrypsin-type	91	382	368	IPR023578 Ras guanine nucleotide exchange factor, domain	32	46
119	IPR000372 Leucine-rich repeat-containing N-terminal	91	198	369	IPR013993 Zinc finger, N-recognin, metazoa	32	35
120	IPR006689 ARF/SAR superfamily	89	307	370	IPR000330 SNF2-related	32	37
121	IPR015919 Cadherin-like	89	851	371	IPR021128 MARVEL-like domain	32	45
122	IPR001440 Tetratricopeptide TPR-1	88	494	372	IPR008996 Cytokine, IL-1-like	32	43
123	IPR001650 Helicase, C-terminal	88	205	373	IPR011012 Longin-like	32	38
124	IPR002126 Cadherin	88	3078	374	IPR018253 Heat shock protein DnaJ, conserved site	32	38
125	IPR008160 Collagen triple helix repeat	88	704	375	IPR017455 Zinc finger, FYVE-related	32	42
126	IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol binding	88	445	376	IPR017850 Alkaline-phosphatase-like, core domain	32	45
127	IPR013105 Tetratricopeptide TPR2	87	256	377	IPR000135 High mobility group, HMG1/HMG2, subgroup	32	122
128	IPR003613 U box domain	87	113	378	IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold	32	43
129	IPR018114 Peptidase S1/S6, chymotrypsin/Hap, active site	86	201	379	IPR001895 Guanine-nucleotide dissociation stimulator CDC25	32	129
130	IPR002035 von Willebrand factor, type A	86	431	380	IPR004843 Metallo-dependent phosphatase	31	38
131	IPR021129 Sterile alpha motif, type 1	85	122	381	IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site	31	34
132	IPR001715 Calponin homology domain	84	557	382	IPR020478 AT hook-like	31	83
133	IPR013091 EGF calcium-binding	83	357	383	IPR000073 Alpha/beta hydrolase fold-1	31	133
134	IPR016130 Protein-tyrosine phosphatase, active site	82	113	384	IPR020067 Frizzled domain	31	140
135	IPR005135 Endonuclease/exonuclease/phosphatase	81	166	385	IPR001320 Ionotropic glutamate receptor	31	81
136	IPR011510 Sterile alpha motif, type 2	81	122	386	IPR000995 Muscarinic acetylcholine receptor	31	146
137	IPR011043 Galactose oxidase/kelch, beta-propeller	81	143	387	IPR000203 GPS domain	31	103
138	IPR013099 Ion transport 2	80	120	388	IPR017979 GPCR, family 3, conserved site	31	80
139	IPR006652 Kelch repeat type 1	80	900	389	IPR000727 Target SNARE coiled-coil domain	30	133
140	IPR003604 Zinc finger, U1-type	79	187	390	IPR003971 Potassium channel, voltage dependent, Kv9	30	158
141	IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype	79	467	391	IPR000798 Ezrin/radixin/moesin family	30	158
142	IPR000219 Dbl homology (DH) domain	78	388	392	IPR013216 Methyltransferase type 11	30	36
143	IPR020894 Cadherin conserved site	78	500	393	IPR001508 NMDA receptor	30	150
144	IPR011498 Kelch repeat type 2	77	307	394	IPR000767 Disease resistance protein	30	75
145	IPR003091 Voltage-dependent potassium channel	77	459	395	IPR004088 K Homology, type 1	30	120
146	IPR002347 Glucose/ribitol dehydrogenase	76	470	396	IPR023795 Protease inhibitor I4, serpin, conserved site	30	47
147	IPR016027 Nucleic acid-binding, OB-fold-like	76	119	397	IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase	30	212
148	IPR000198 Rho GTPase-activating protein domain	76	279	398	IPR003299 Flagellar calcium-binding protein calflagin	30	101
149	IPR001828 Extracellular ligand-binding receptor	76	100	399	IPR001589 Actinin-type, actin-binding, conserved site	30	64
150	IPR019787 Zinc finger, PHD-finger	75	217	400	IPR008037 Proteinase inhibitor I19, pacifastin	30	74
151	IPR000357 HEAT	75	273	401	IPR002017 Spectrin repeat	30	295
152	IPR009072 Histone-fold	75	83	402	IPR018039 Intermediate filament protein, conserved site	29	42
153	IPR000884 Thrombospondin, type 1 repeat	73	1320	403	IPR003990 Pancreatitis-associated protein	29	102
154	IPR002198 Short-chain dehydrogenase/reductase SDR	70	342	404	IPR006207 Cystine knot, C-terminal	29	85
155	IPR019786 Zinc finger, PHD-type, conserved site	69	95	405	IPR011162 MHC classes I/II-like antigen recognition protein	29	42
156	IPR001991 Sodium:dicarboxylate symporter	68	281	406	IPR017956 AT hook, DNA-binding motif	29	81
157	IPR000108 Neutrophil cytosol factor 2 p67phox	68	268	407	IPR000418 Ets	29	300
158	IPR000961 AGC-kinase, C-terminal	67	86	408	IPR003649 B-box, C-terminal	29	38
159	IPR001723 Steroid hormone receptor	67	379	409	IPR011017 TRASH	29	103
160	IPR019749 Band 4.1 domain	67	92	410	IPR002394 Nicotinic acetylcholine receptor	29	140
161	IPR008946 Nuclear hormone receptor, ligand-binding	67	81	411	IPR002348 Interleukin 1/heparin-binding growth factor	28	202
162	IPR018378 C-type lectin, conserved site	67	114	412	IPR002867 Zinc finger, C6HC-type	28	75
163	IPR000536 Nuclear hormone receptor, ligand-binding, core	66	159	413	IPR001846 von Willebrand factor, type D domain	28	145
164	IPR020477 C2 region	66	233	414	IPR002999 Tudor domain	28	47
165	IPR004031 PMP-22/EMP/MP20/Claudin	66	74	415	IPR000772 Ricin B lectin	28	99
166	IPR006029 Neurotransmitter-gated ion-channel transmembrane domain	66	125	416	IPR003915 Polycystic kidney disease type 2 protein	28	90
167	IPR001628 Zinc finger, nuclear hormone receptor-type	66	528	417	IPR019747 FERM conserved site	28	55
168	IPR019748 FERM central domain	65	130	418	IPR017933 Glutathione S-transferase/chloride channel, C-terminal	28	37
169	IPR001671 Melanocortin/ACTH receptor	65	223	419	IPR002030 Mitochondrial brown fat uncoupling protein	28	140
170	IPR006202 Neurotransmitter-gated ion-channel ligand-binding	65	145	420	IPR000233 Cadherin, cytoplasmic domain	28	38
171	IPR009071 High mobility group, superfamily	64	89	421	IPR009050 Globin-like	28	38
172	IPR000248 Angiotensin II receptor	64	335	422	IPR003556 Claudin-14	28	84
173	IPR006201 Neurotransmitter-gated ion-channel	64	410	423	IPR006586 ADAM, cysteine-rich	28	48
174	IPR010978 tRNA-binding arm	64	79	424	IPR017976 Endoglin/CD105 antigen subgroup	28	115
175	IPR000299 FERM domain	63	84	425	IPR008997 Ricin B-related lectin	28	37
176	IPR017981 GPCR, family 2-like	63	75	426	IPR000863 Sulfotransferase domain	28	35
177	IPR001128 Cytochrome P450	63	418	427	IPR023313 Ubiquitin-conjugating enzyme, active site	28	33
178	IPR016060 Complement control module	63	247	428	IPR001610 PAC motif	28	33
179	IPR011016 Zinc finger, RING-CH-type	62	73	429	IPR011527 ABC transporter, transmembrane domain, type 1	28	38
180	IPR003597 Immunoglobulin C1-set	62	167	430	IPR001164 Arf GTPase activating protein	28	291
181	IPR003659 Plexin/semaphorin/integrin	62	140	431	IPR013830 Esterase, SGNH hydrolase-type	28	28
182	IPR001791 Laminin G domain	61	286	432	IPR001111 Transforming growth factor-beta, N-terminal	28	38
183	IPR002401 Cytochrome P450, E-class, group I	61	498	433	IPR000463 Cytosolic fatty-acid binding	28	97
184	IPR012337 Ribonuclease H-like	61	66	434	IPR017990 Connexin, conserved site	28	51
185	IPR000324 Vitamin D receptor	61	170	435	IPR006594 LisH dimerisation motif	27	58
186	IPR018000 Neurotransmitter-gated ion-channel, conserved site	61	84	436	IPR000003 Retinoid X receptor	27	174
187	IPR001609 Myosin head, motor domain	61	487	437	IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain	27	96
188	IPR006187 Claudin	60	191	438	IPR001506 Peptidase M12A, astacin	27	182
189	IPR003954 RNA recognition motif domain, eukaryote	60	132	439	IPR000253 Forkhead-associated (FHA) domain	27	84
190	IPR009134 Tyrosine-protein kinase, vascular endothelial growth factor receptor (VEGFR), N-terminal	60	204	440	IPR008906 HAT dimerisation	27	27
191	IPR011705 BTB/Kelch-associated	60	83	441	IPR008280 Tubulin/FtsZ, C-terminal	27	32
192	IPR009030 Growth factor, receptor	59	96	442	IPR003960 ATPase, AAA-type, conserved site	27	35
193	IPR018108 Mitochondrial substrate/solute carrier	59	502	443	IPR000068 GPCR, family 3, extracellular calcium-sensing receptor-related	27	116
194	IPR000169 Peptidase, cysteine peptidase active site	59	102	444	IPR000585 Hemopexin/matrixin	27	38
195	IPR001810 F-box domain, cyclin-like	58	175	445	IPR011704 ATPase, AAA-5	27	45
196	IPR023214 HAD-like domain	58	75	446	IPR000651 Ras-like guanine nucleotide exchange factor, N-terminal	27	105
197	IPR002492 Transposase, Tc1-like	58	58	447	IPR001060 Fps/Fes/Fer/CIP4 homology	27	89
198	IPR001623 Heat shock protein DnaJ, N-terminal	57	267	448	IPR002078 RNA polymerase sigma factor 54, interaction	27	30
199	IPR002403 Cytochrome P450, E-class, group IV	56	348	449	IPR000488 Death	27	86
200	IPR000832 GPCR, family 2, secretin-like	56	392	450	IPR006703 AIG1	27	39
201	IPR011029 DEATH-like	56	71	451	IPR018487 Hemopexin/matrixin, repeat	27	259
202	IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type	55	546	452	IPR000591 DEP domain	26	100
203	IPR000910 High mobility group, HMG1/HMG2	55	221	453	IPR013806 Kringle-like fold	26	49
204	IPR008917 Eukaryotic transcription factor, Skn-1-like, DNA-binding	55	64	454	IPR003347 Transcription factor jumonji/aspartyl beta-hydroxylase	26	30
205	IPR002049 EGF-like, laminin	55	897	455	IPR000421 Coagulation factor 5/8 type, C-terminal	26	197
206	IPR008983 Tumour necrosis factor-like	54	64	456	IPR001594 Zinc finger, DHHC-type, palmitoyltransferase	26	67
207	IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular	54	158	457	IPR022812 Dynamin	26	121
208	IPR002232 5-Hydroxytryptamine 6 receptor	54	172	458	IPR001760 Opsin	26	102
209	IPR013763 Cyclin-like	54	165	459	IPR020568 Ribosomal protein S5 domain 2-type fold	26	34
210	IPR017972 Cytochrome P450, conserved site	54	65	460	IPR013164 Cadherin, N-terminal	26	32
211	IPR000104 Antifreeze protein, type I	53	138	461	IPR013655 PAS fold-3	26	32
212	IPR012680 Laminin G, subdomain 2	53	141	462	IPR000190 AT1 angiotensin II receptor	26	83
213	IPR001683 Phox homologous domain	53	256	463	IPR020845 AMP-binding, conserved site	26	32
214	IPR020457 Zinc finger, B-box, chordata	53	128	464	IPR001876 Zinc finger, RanBP2-type	26	172
215	IPR017978 GPCR, family 3, C-terminal	53	129	465	IPR020590 Guanylate kinase, conserved site	26	37
216	IPR002067 Mitochondrial carrier protein	53	366	466	IPR008080 Parvalbumin	26	92
217	IPR001202 WW/Rsp5/WWP	53	505	467	IPR008974 TRAF-like	26	52
218	IPR003912 Protease-activated receptor	53	206	468	IPR018933 Netrin module, non-TIMP type	25	53
219	IPR003131 Potassium channel, voltage dependent, Kv, tetramerisation	52	66	469	IPR013767 PAS fold	25	36
220	IPR009060 UBA-like	52	65	470	IPR001969 Peptidase aspartic, active site	25	34
221	IPR017853 Glycoside hydrolase, superfamily	52	73	471	IPR003008 Tubulin/FtsZ, GTPase domain	25	60
222	IPR007125 Histone core	52	55	472	IPR001491 Thrombomodulin	25	80
223	IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase	52	196	473	IPR006076 FAD dependent oxidoreductase	25	31
224	IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit	52	265	474	IPR017995 Homeobox protein, antennapedia type	25	62
225	IPR003959 ATPase, AAA-type, core	52	65	475	IPR001638 Extracellular solute-binding protein, family 3	25	32
226	IPR008984 SMAD/FHA domain	51	67	476	IPR002870 Peptidase M12B, propeptide	25	28
227	IPR000159 Ras-association	51	164	477	IPR020837 Fibrinogen, conserved site	25	31
228	IPR002113 Adenine nucleotide translocator 1	51	230	478	IPR000261 EPS15 homology (EH)	25	64
229	IPR016160 Aldehyde dehydrogenase, conserved site	51	82	479	IPR000998 MAM domain	25	234
230	IPR008967 p53-like transcription factor, DNA-binding	51	60	480	IPR018297 Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site	25	40
231	IPR000725 Olfactory receptor	51	285	481	IPR013027 FAD-dependent pyridine nucleotide-disulphide oxidoreductase	25	90
232	IPR017892 Protein kinase, C-terminal	50	67	482	IPR001368 TNFR/CD27/30/40/95 cysteine-rich region	25	179
233	IPR000436 Sushi/SCR/CCP	50	537	483	IPR000182 GCN5-related N-acetyltransferase (GNAT) domain	24	31
234	IPR017871 ABC transporter, conserved site	50	66	484	IPR002373 cAMP/cGMP-dependent protein kinase	24	118
235	IPR000337 GPCR, family 3	50	578	485	IPR002209 Heparin-binding growth factor/Fibroblast growth factor	24	107
236	IPR011038 Calycin-like	50	59	486	IPR004073 GPCR, family 3, vomeronasal receptor, type 2	24	162
237	IPR015424 Pyridoxal phosphate-dependent transferase, major domain	50	68	487	IPR022272 Lipocalin conserved site	24	29
238	IPR001752 Kinesin, motor domain	50	368	488	IPR003607 Metal-dependent phosphohydrolase, HD domain	24	33
239	IPR018499 Tetraspanin	49	65	489	IPR008250 ATPase, P-type, ATPase-associated domain	24	37
240	IPR001125 Recoverin	49	247	490	IPR006644 Dystroglycan-type cadherin-like	24	30
241	IPR005829 Sugar transporter, conserved site	49	95	491	IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved site	24	30
242	IPR011700 Basic leucine zipper	49	55	492	IPR001630 cAMP response element binding (CREB) protein	24	78
243	IPR000225 Armadillo	49	588	493	IPR007111 NACHT nucleoside triphosphatase	24	26
244	IPR015940 Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote	48	114	494	IPR005816 Secreted growth factor Wnt protein	23	140
245	IPR000496 Bradykinin receptor	48	204	495	IPR017983 GPCR, family 2, secretin-like, conserved site	23	44
246	IPR016135 Ubiquitin-conjugating enzyme/RWD-like	48	60	496	IPR001605 Spectrin/pleckstrin-like	23	68
247	IPR006020 Phosphotyrosine interaction domain	48	155	497	IPR005817 Wnt superfamily	23	58
248	IPR011072 HR1 rho-binding repeat	48	95	498	IPR013517 FG-GAP	23	64
249	IPR016044 Filament	48	67	499	IPR000217 Tubulin	23	234
250	IPR008952 Tetraspanin, EC2 domain	47	62	500	IPR003034 DNA-binding SAP	23	67

View top 40 InterPro hits